Cytotoxic Effect of the Alcoholic Extract of Conocarpus erectus Leaves on MDA-MB 231 and MCF7 Breast Cancer Cell Lines

Currently, there is a growing interest in medicinal plants extracts as some have shown antitumor potential. The goal of this study was to test the anticancer activity methanol extract Conocarpous erectus leaves breast cancer cells. Cytotoxicity tested vitro on cell lines, MCF7 [Estrogen receptor + (ER+)] and MDA-MB231 - (ER-)], addition normal fibroblast cells (REF). MTT assay utilized measure growth inhibitory effects after 48 hours exposure extracts. Viability results indicated that were sensitive (GI50 = 56.1µg/ml).However, no sensitivity seen both REF (GI50>100 µg/ml). Interestingly associated with significant reduction number size. It can be concluded from may provide candidate therapy against not linked ER expression. No effect observed